ALPHAGAN

This medicine contains the active ingredient brimonidine, which is an alpha-adrenergic agonist. These medicines lower the increased pressure in the eye by reducing the amount of fluid. This medicine is prescribed for the treatment of open angle glaucoma (ocular hypertension) which causes damage to the optic nerve and gradual loss of vision.

Is Brimonidine suitable for me?

Brimonidine is not suitable for everyone. Do not use it

• if you are allergic to brimonidine or to other ingredients of this medicine
• if you are taking monoamine oxidase (MAO) inhibitors or certain antidepressants. You must inform your doctor if you are taking any antidepressant drug.
• if you are breast-feeding.
• in infants/babies (under 2 years)

 In particular, you must tell the doctor if you:

• suffer or have suffered from depression, reduced mental capacity, reduced blood supply to the brain, heart problems, a disturbed blood supply of the limbs or a blood pressure disorder
• have or have had in the past kidney or liver problems
• are giving it to a child between the age of 2 and 12 years
• are pregnant, trying to get pregnant or breastfeeding

Brimonidine interacts with other medicines. It is most important that you tell the doctor all the medications and herbal supplements that you are currently taking.

See the package leaflet for a complete list of possible contraindications and warnings.

How should I take Brimonidine?

This medicine is available in form of eye drops, solution.

You should take brimonidine exactly as instructed by your doctor or pharmacist.

• The usual dose is one drop twice daily in the affected eye(s), every 12 hours.

Do not use more of it, do not use it more often, or do not use it for a longer time than your doctor instructed. Do not miss any doses and apply the medicine at the same time each day. Do not apply two doses together if you miss a dose.

Read the information leaflet provided with your medication for additional information. Talk to your doctor if you have any additional questions.

What are Brimonidine side effects?

Like all medicines brimonidine can cause side effects, including:

Affecting the eye

Very common:

• irritation of the eye (eye redness, burning, stinging)
• blurred vision
• an allergic reaction in the eye

Common:

• local irritation (inflammation and swelling of the eyelid, sticky eyes, pain and tearing)
• sensitivity to light
• erosion on the surface of the eye and staining
• eye dryness
• whitening of the see-through layer which covers the surface of the eye
• abnormal vision
• inflammation of the see-through layer which covers the surface of the eye

Affecting the body

Very common:

• headache
• dry mouth
• tiredness/drowsiness

Common:

• dizziness
• cold-like symptoms
• symptoms involving the stomach and digestion
• abnormal taste
• general weakness

Consult a doctor if the side effects are severe. See the package leaflet for a complete list of side effects.